Noticed today that Gmail has a nice spam feature when you report an email sent by a certain company or a mailing-list. When you click on the spam button, Gmail automatically asks you whether you want to send an unsubscribe request to the email sender.
In my opinion this is a really nice feature, in case you haven't used it, do try it the next time you get emails from lists that you never subscribed to!
More info here:
http://support.google.com/mail/bin/answer.py?hl=en&ctx=mail&answer=80405